The rapid growth of space applications has led the space industry to explore novel, innovative platforms for onboard data processing. The European BRAVE family of FPGAs is considered a promising solution in the generally limited pool of radiation-hardened devices. Our current work develops a methodology to drive the evaluation of the BRAVE EDA tools and devices. The paper focuses on NG-LARGE, ie, the largest FPGA of the 65nm RHBD technology of NanoXplore. The proposed approach consists of numerous inter-dependent steps for assessing the entire FPGA design flow, including highperformance benchmarking with HDL IPs from ongoing Vision-Based Navigation activities, testing on actual HW, as well as comparisons vs state-of-the-art FPGAs.