… drug discovery pipelines; but screening was still in the setting of complex disease biology, …
or indirectly from such early 'systems biology'-based drug discovery. In the interest of speed …

… of complex systems. The emergence of systems biology is a timely occurrence for drug
discovery… As the time and expense required to bring new drugs to market continually escalate, it is …

… system biology 14, 15. Another coarse grain organ model that illustrates the potential of systems
biology in drug discovery … The results actually suggest that drug discovery efforts should …

… In particular, we claim that network biology will play a central part in the … system biology
strategies are more likely to have an immediate contribution: predictive toxicology and drug …

… to ameliorate or normalize the system. This review discusses how translational research and
systems biology together could improve global understanding of drug targets, suggest new …

… One of the primary aims of drug discovery over the last 30 years has been to design drugs
against … This approach to drug discovery has not met with huge success, largely because it …

… first systems biology text to focus on how systems biology can be specifically applied to
enhance drug discovery and … Other texts on systems biology to date have focused on particular …

… systems biology is a phenotypic drug discovery approach that incorporates the richness of
human disease biology … BioMAP ® systems, developed on cell systems biology principles, are …

… Systems biology can be briefly defined as the integration of … The tenet of systems biology
has been described as … In what appears a sweeping rebuttal to reductionism, systems biology …

… that pertain closely to metabolic systems biology are cheminformatics and chemical genetics…
be applied to the computational systems biology of natural metabolic systems, and we need …