过去一年中添加的文章,按日期排序
ASO-enhancement of TARDBP exitron splicing mitigates TDP-43 proteinopathies
T Yamagishi, S Koide, G Toyama, A Washida… - bioRxiv, 2024 - biorxiv.org
3 天前 - … modulation in a TDP-43 proteinopathy model independent of TDP-43 overexpression,
we … Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. …
we … Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. …
[HTML][HTML] Biophysical characterization of the phase separation of TDP-43 devoid of the C-terminal domain
T Staderini, A Bigi, C Lagrève, I Marzi… - Cellular & Molecular …, 2024 - Springer
12 天前 - … of LLPS of PrLD-less TDP-43 is distinct from that of the TDP-43 PrLD and also from
that … of the forces governing phase separation of full-length TDP-43 and its two fragments. …
that … of the forces governing phase separation of full-length TDP-43 and its two fragments. …
Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study
A Murakami, S Koga, S Fujioka, AE White… - Brain …, 2024 - Wiley Online Library
14 天前 - … with TDP-43 pathology in the presence or absence of frontotemporal lobar degeneration.
… -term memory loss, frontotemporal dementia, or other types of dementia recorded by a …
… -term memory loss, frontotemporal dementia, or other types of dementia recorded by a …
TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro
H Meng, X Long, M Jiang, Y Miao, H Du, T Zhang, Z Ma… - bioRxiv, 2024 - biorxiv.org
15 天前 - … Mutations in the DNA/RNA-binding protein 43 (TDP-43) can cause amyotrophic
lateral sclerosis and frontotemporal dementia (ALS-FTD). As an RNA-binding protein, TDP-43 …
lateral sclerosis and frontotemporal dementia (ALS-FTD). As an RNA-binding protein, TDP-43 …
Plasma extracellular vesicle biomarkers for frontotemporal dementia and related disorders
L Kiani - Nature Reviews Neurology, 2024 - nature.com
17 天前 - … Conversely, TDP-43 FTD and ALS samples had elevated levels of TDP-43 in EVs,
… “We found that the combination of plasma EV TDP-43 and EV tau isoform ratio discriminates …
… “We found that the combination of plasma EV TDP-43 and EV tau isoform ratio discriminates …
… tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia
MS Baghel, GD Burns, M Tsapatsis… - bioRxiv, 2024 - biorxiv.org
26 天前 - … lateral sclerosis (ALS) and frontotemporal dementia (FTD), coexists with tauopathy
… dementias (MEDs), including Alzheimer’s Disease (AD). While such co-pathology of TDP-43 …
… dementias (MEDs), including Alzheimer’s Disease (AD). While such co-pathology of TDP-43 …
Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C
D Arseni, T Nonaka, MH Jacobsen, AG Murzin… - bioRxiv, 2024 - biorxiv.org
29 天前 - … TDP-43 in the brain and are associated with different frontotemporal dementias (FTD)11. …
Owing to our finding of heteromeric filaments composed of both ANXA11 and TDP-43 …
Owing to our finding of heteromeric filaments composed of both ANXA11 and TDP-43 …
Research trends and hotspots for frontotemporal dementia from 2000 to 2022: A bibliometric analysis
X Chen, Y Chen, B Ni, C Huang - Frontiers in Neurology - frontiersin.org
29 天前 - … research hotspots in this field were the clinical diagnostic criteria, subdivision,
and pathological mechanism of FTD, such as tau protein, chromosome 17, progranulin, TDP-43, …
and pathological mechanism of FTD, such as tau protein, chromosome 17, progranulin, TDP-43, …
Genetika frontotemporalnih demencija
I Tomaš - 2024 - repozitorij.mef.unizg.hr
30 天前 - … background of frontotemporal dementia involves … i TDP-43, istraživala se
uključenost FUS-a u FTD patologiju, te je otkriveno da je većina slučajeva FTLD bez tau i TDP-43 …
uključenost FUS-a u FTD patologiju, te je otkriveno da je većina slučajeva FTLD bez tau i TDP-43 …
Alterations to metabolic hormones in amyotrophic lateral sclerosis and frontotemporal dementia postmortem human tissue
RAK Atkinson, JM Collins, J Sreedharan… - … of Neuropathology & …, 2024 - academic.oup.com
30 天前 - … degeneration and TDP-43 associated pathology. The increase in LEPR gene
expression observed in the current study may be due to restricted entry of leptin into the brain and/…
expression observed in the current study may be due to restricted entry of leptin into the brain and/…