… , and therapeutic resistance of breast and other cancers, but its roles … of TTK in triple negative
breast cancer (TNBC), and found that higher TTK expression correlated with mesenchymal …

TTK promotes HER2 + breast cancer cell migration, apoptosis, and resistance to targeted
therapy by modulating the Akt/mTOR axis | Journal of Cancer Research and Clinical Oncology …

… expression of TTK and known epithelial–mesenchymal transition (… invasion in triple-negative
breast cancer cells [10]. In ovarian … We verified that TTK enhances EMT phenotypes and …

… In breast cancer, CDC20 was reported to bind and promote proteasomal degradation of
SMAR1, thus promoting migration and invasion capabilities of cancer cells (31). In glioma, …

… Moreover, in mitosis, TTK promotes phosphorylation of bloom syndrome protein (BLM)
and subsequent interaction of BLM with polo-like kinase 1, ensuring accurate chromosome …

… TTK is overexpressed in many cancers, promoting tumor growth in glioblastoma, breast cancer
and other cancers … to promote cell migration and epithelial-mesenchymal transition (EMT)…

… Anticancer activity was assessed in vitro using cell growth … , using mouse models of triple
negative breast cancer (TNBC). … ) of the anaphase-promoting complex, which promotes mitotic …

… Mtp53 acts as an oncogene and promotes the transformation from normal cells into tumor …
from mesenchymal to epithelial cells, and miR-200c is often lost in basal breast tumor cells. …

… Heterogeneity at the invasion front of triple negative breast cancer cells. … based on gene
expression analysis, including two basal-like (BL1 and BL2), two mesenchymal (M and MSL), …

… Moreover, Hec1 interacts with TTK through a mechanism in which Aurora B phosphorylates
… enhances the localization of TTK to the kinetochore, demonstrating the direct binding of TTK …