Targeting TGF beta signaling for cancer therapy
S Iyer, ZG Wang, M Akhtari, W Zhao… - … biology & therapy, 2005 - Taylor & Francis
… approaching cancer therapy with an eye to the inhibition of TGFβ signaling. TGFβ SIGNALING:
… years promise to better our understanding of targeting TGFβ signaling for cancer therapy. …
… years promise to better our understanding of targeting TGFβ signaling for cancer therapy. …
Targeting TGF-β signaling in cancer
S Colak, P Ten Dijke - Trends in cancer, 2017 - cell.com
… for targeting TGF-β signaling in cancer and … TGF-β signaling blockade on tumor and stromal
cells, as well as biomarkers that can predict the efficacy of TGF-β inhibitors in cancer patients…
cells, as well as biomarkers that can predict the efficacy of TGF-β inhibitors in cancer patients…
Molecular pathways: targeting the TGF-β pathway for cancer therapy
AL Smith, TP Robin, HL Ford - Clinical Cancer Research, 2012 - AACR
… to TGF-β signaling. The clinical studies under way have already shown TGF-β as a promising
target for cancer therapy… be a powerful means to enhance the outcomes of these therapies. …
target for cancer therapy… be a powerful means to enhance the outcomes of these therapies. …
Targeting TGF-β signaling in cancer
LH Katz, Y Li, JS Chen, NM Muñoz… - … on therapeutic targets, 2013 - Taylor & Francis
… data on targeting TGF-β pathway for cancer treatment is … -TGF-β based treatment and other
options targeting activated pathways in tumors where the TGF-β tumor suppressor pathway is …
options targeting activated pathways in tumors where the TGF-β tumor suppressor pathway is …
TGF-beta signaling in cancer treatment
I Fabregat, J Fernando, J Mainez… - Current pharmaceutical …, 2014 - ingentaconnect.com
… signaling in the regulation of tumorigenesis and we will dissect how targeting the TGF-!
pathway may contribute to fight against cancer. Keywords: …
pathway may contribute to fight against cancer. Keywords: …
[HTML][HTML] Targeting the transforming growth factor-β signaling in cancer therapy
YY Sheen, MJ Kim, SA Park, SY Park… - … & therapeutics, 2013 - ncbi.nlm.nih.gov
… suppression and promotion by TGF-β. In the last part of the review, the data on targeting
TGF-β pathway for cancer treatment is assessed. The TGF-β inhibitors in pre-clinical studies, …
TGF-β pathway for cancer treatment is assessed. The TGF-β inhibitors in pre-clinical studies, …
[HTML][HTML] Targeting TGF-β signal transduction for fibrosis and cancer therapy
D Peng, M Fu, M Wang, Y Wei, X Wei - Molecular cancer, 2022 - Springer
… of TGF-β and its downstream molecules in the progression of fibrosis and cancers, therapeutics
targeting TGF-β signaling … , the development of TGF-β therapeutics has lagged. In this …
targeting TGF-β signaling … , the development of TGF-β therapeutics has lagged. In this …
[HTML][HTML] Targeting the TGFβ pathway for cancer therapy
C Neuzillet, A Tijeras-Raballand, R Cohen… - … & therapeutics, 2015 - Elsevier
… targeted strategy. In this review, we focus on the TGFβ pathway as a target for cancer therapy…
of the roles played by this pathway and its deregulation in cancer, at the cancer cell and …
of the roles played by this pathway and its deregulation in cancer, at the cancer cell and …
[HTML][HTML] Complexities of TGF-β targeted cancer therapy
EC Connolly, J Freimuth, RJ Akhurst - International journal of …, 2012 - ncbi.nlm.nih.gov
… is often elevated in human tumors, and thus a clinical target. This has led to the development
of a range of anti-TGF-β-signaling drugs for cancer therapy. The four major classes of TGF-…
of a range of anti-TGF-β-signaling drugs for cancer therapy. The four major classes of TGF-…
Inhibition of TGFβ signaling in cancer therapy
CL Arteaga - Current opinion in genetics & development, 2006 - Elsevier
… Transforming growth factor β (TGFβ) was initially discovered acting as an oncogene in
the … its potential as a target for cancer therapy. Subsequent studies showed that TGFβ is a …
the … its potential as a target for cancer therapy. Subsequent studies showed that TGFβ is a …