Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of
the key factors for the development of atherosclerosis. Nonoxidized LDL have a low affinity
for macrophages, so they are not themselves a risk factor. However, lowering LDL levels is a
common clinical practice to reduce oxidation and the risk of major events in patients with
cardiovascular diseases (CVD). Atherosclerosis starts with dysfunctional changes in the …