Temporal analysis of active and passive transport in living cells
D Arcizet, B Meier, E Sackmann, JO Rädler… - Physical review letters, 2008 - APS
D Arcizet, B Meier, E Sackmann, JO Rädler, D Heinrich
Physical review letters, 2008•APSThe cellular cytoskeleton is a fascinating active network, in which Brownian motion is
intercepted by distinct phases of active transport. We present a time-resolved statistical
analysis dissecting phases of directed motion out of otherwise diffusive motion of tracer
particles in living cells. The distribution of active lifetimes is found to decay exponentially
with a characteristic time τ¯ A= 0.65 s. The velocity distribution of active events exhibits
several peaks, in agreement with a discrete number of motor proteins acting collectively.
intercepted by distinct phases of active transport. We present a time-resolved statistical
analysis dissecting phases of directed motion out of otherwise diffusive motion of tracer
particles in living cells. The distribution of active lifetimes is found to decay exponentially
with a characteristic time τ¯ A= 0.65 s. The velocity distribution of active events exhibits
several peaks, in agreement with a discrete number of motor proteins acting collectively.
The cellular cytoskeleton is a fascinating active network, in which Brownian motion is intercepted by distinct phases of active transport. We present a time-resolved statistical analysis dissecting phases of directed motion out of otherwise diffusive motion of tracer particles in living cells. The distribution of active lifetimes is found to decay exponentially with a characteristic time . The velocity distribution of active events exhibits several peaks, in agreement with a discrete number of motor proteins acting collectively.
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