The Impact of Different Patterns of Residual Disease on Long-Term Oncological Outcomes in Breast Cancer Patients Treated with Neo-Adjuvant Chemotherapy
C Tinterri, B Fernandes, A Zambelli, A Sagona… - Cancers, 2024 - mdpi.com
Simple Summary We investigated the predictive factors for different patterns of residual
disease in the breast after neo-adjuvant chemotherapy and compared the long-term
outcomes between the scattered versus the circumscribed pattern. A total of 219 histologic
sections of postoperative surgical specimens were evaluated. Two independent predictive
factors for the circumscribed pattern were identified: discontinuation of neo-adjuvant
chemotherapy cycles and a tumor size> 18 mm. Over a median follow-up of 74.7 months …
disease in the breast after neo-adjuvant chemotherapy and compared the long-term
outcomes between the scattered versus the circumscribed pattern. A total of 219 histologic
sections of postoperative surgical specimens were evaluated. Two independent predictive
factors for the circumscribed pattern were identified: discontinuation of neo-adjuvant
chemotherapy cycles and a tumor size> 18 mm. Over a median follow-up of 74.7 months …
[引用][C] The impact of different patterns of residual disease on long-term oncological outcomes in breast cancer patients treated with neo-adjuvant chemotherapy
D Gentile, B Fernandes, A Zambelli, SS Darwish… - European Journal of …, 2024 - ejso.com
Methods: 209 post-operative surgical specimens of BC patients treated with NAC at the
Breast Unit of IRCCS Humanitas Research Hospital (Milan, Italy) were reviewed. Patients
were divided into two groups: scattered versus circumscribed. A multivariate logistic
regression analysis was performed to identify predictive factors for residual disease.
Disease-free survival (DFS), distant disease-free survival (DDFS), and overall survival (OS)
were analysed. Results: The majority of the patients were treated with mastectomy (n= 130 …
Breast Unit of IRCCS Humanitas Research Hospital (Milan, Italy) were reviewed. Patients
were divided into two groups: scattered versus circumscribed. A multivariate logistic
regression analysis was performed to identify predictive factors for residual disease.
Disease-free survival (DFS), distant disease-free survival (DDFS), and overall survival (OS)
were analysed. Results: The majority of the patients were treated with mastectomy (n= 130 …
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