Role of Sodium‐Calcium Exchanger (Ncx1) in Embryonic Heart Development: A Transgenic Rescue?
SJ Conway, A KRUZYNSKA‐FREJTAG… - Annals of the New …, 2002 - Wiley Online Library
… 2+ homeostasis in early embryonic heart development in mouse. (a) Ventricular Ca 2+
transients in a spontaneously beating heart tube from a Ncx1 lacZ /+ embryo at 9.5 dpc. Caffeine (…
transients in a spontaneously beating heart tube from a Ncx1 lacZ /+ embryo at 9.5 dpc. Caffeine (…
Developmental regulation of Na+/H+exchanger expression in fetal and neonatal mice
CV Rieder, L Fliegel - … Journal of Physiology-Heart and …, 2002 - journals.physiology.org
… development, we used transgenic mice expressing a GFP reporter coupled to the mouse Na
+ /H + exchanger … of the upstream elements that are important for expression in mammalian …
+ /H + exchanger … of the upstream elements that are important for expression in mammalian …
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart
M Reppel, BK Fleischmann, H Reuter… - Cardiovascular …, 2007 - academic.oup.com
… development and function demonstrated by the … embryonic death of NCX-null embryos. It
was therefore the aim of our study to identify key functional regulators of the embryonic NCX. …
was therefore the aim of our study to identify key functional regulators of the embryonic NCX. …
Na, K-ATPase is essential for embryonic heart development in the zebrafish
X Shu, K Cheng, N Patel, F Chen, E Joseph, HJ Tsai… - 2003 - journals.biologists.com
… function through interaction with the Na + /Ca 2+ exchanger. … in the mouse suggest that
Na,K-ATPase activity is important during embryogenesis, as α1 homozygous mice are embryonic …
Na,K-ATPase activity is important during embryogenesis, as α1 homozygous mice are embryonic …
Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart
S Siedner, M Krüger, M Schroeter… - The Journal of …, 2003 - Wiley Online Library
… , respectively; E19.5 after exchange and Adult after exchange: skinned ventricular fibres …
a crucial role for TnI in Ca 2+ -regulated force development during murine heart development. …
a crucial role for TnI in Ca 2+ -regulated force development during murine heart development. …
Myocardial function with reduced expression of the sodium-calcium exchanger
MC Jordan, SA Henderson, T Han, MC Fishbein… - Journal of cardiac …, 2010 - Elsevier
… In summary, the 50% reduction of the exchanger in all the myocytes of HG-KO mice is
associated with normal myocardial structure and function at baseline, tolerance to pressure …
associated with normal myocardial structure and function at baseline, tolerance to pressure …
Slc26a6: a cardiac chloride–hydroxyl exchanger and predominant chloride–bicarbonate exchanger of the mouse heart
BV Alvarez, DM Kieller, AL Quon… - The Journal of …, 2004 - Wiley Online Library
… anion exchange proteins in mouse heart, by quantitative real time RT-PCR. Bicarbonate–anion
exchangers … Cl − –HCO 3 − and Cl − –OH − exchange activity of SLC26A6 and AE3 were …
exchangers … Cl − –HCO 3 − and Cl − –OH − exchange activity of SLC26A6 and AE3 were …
Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP
D Harzheim, KH Pfeiffer, L Fabritz, E Kremmer… - The EMBO …, 2008 - embopress.org
… mice that harbour a single amino‐acid exchange (R669Q) in the CNBD of the HCN4 channel.
This arginine residue is crucial … of mice via homologous recombination in embryonic stem …
This arginine residue is crucial … of mice via homologous recombination in embryonic stem …
Expressional analysis of the cardiac Na–Ca exchanger in rat development and senescence
MU Koban, AFM Moorman, J Holtz… - Cardiovascular …, 1998 - academic.oup.com
… Embryos were obtained from pregnant decapitated rats after … We have examined rat cardiac
Na–Ca exchanger mRNA and … spatially during fetal and neonatal cardiac development. The …
Na–Ca exchanger mRNA and … spatially during fetal and neonatal cardiac development. The …
Onset of cardiac function during early mouse embryogenesis coincides with entry of primitive erythroblasts into the embryo proper
RP Ji, CKL Phoon, O Aristizábal, KE McGrath… - Circulation …, 2003 - Am Heart Assoc
… time points and basic physiology of the very early mouse embryonic circulation using …
developed in our laboratory that allows in utero study of the embryonic mouse circulation. …
developed in our laboratory that allows in utero study of the embryonic mouse circulation. …