Both nicotine and various non-nicotine smoking factors are believed to contribute to tobacco
addiction but their relative roles remain incompletely understood. This study aimed to help
clarify these roles by examining acute interactions between nicotine and denicotinized
tobacco (DT). During two randomized blinded sessions, the effects of a quick-release 4 mg
nicotine lozenge (NL) versus placebo lozenge (PL) on the subjective and behavioural
responses to DT were examined in 27 (14 men) dependent, daily smokers. Participants …