The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery: retracted
SS Reuben, A Buvanendran, JS Kroin… - Anesthesia & …, 2006 - journals.lww.com
SS Reuben, A Buvanendran, JS Kroin, K Raghunathan
Anesthesia & Analgesia, 2006•journals.lww.com… In this trial, we assessed the analgesic efficacy of administering perioperative celecoxib,
pregabalin, or both after spinal fusion surgery. … This study revealed that the perioperative
administration of the combination of celecoxib and pregabalin resulted in improved
analgesia compared with either analgesic drug alone after spinal fusion surgery. This
combination produced a significant reduction in pain scores and in morphine use during the
first 24 postoperative hours. The …
pregabalin, or both after spinal fusion surgery. … This study revealed that the perioperative
administration of the combination of celecoxib and pregabalin resulted in improved
analgesia compared with either analgesic drug alone after spinal fusion surgery. This
combination produced a significant reduction in pain scores and in morphine use during the
first 24 postoperative hours. The …
IMPLICATIONS: The perioperative administration of a combination of celecoxib and pregabalin improved analgesia and caused fewer side effects than either analgesic drug alone after spinal fusion surgery.
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