The changing landscape of motor neuron disease imaging: the transition from descriptive studies to precision clinical tools
P Bede, G Querin, PF Pradat - Current opinion in neurology, 2018 - journals.lww.com
P Bede, G Querin, PF Pradat
Current opinion in neurology, 2018•journals.lww.com… We are witnessing a conceptual paradigm shift in the role of imaging which cannot be merely
explained by technological advances. Imaging in MND has traditionally served as a descriptive
academic tool to characterize group-level pathological features in vivo. These attempts have
been typically hampered by sample size limitations, reliance on convenience samples,
emphasis on focal structural … Spinal imaging has long been one of the least explored
frontiers of MND imaging despite disease-defining lower motor neuron (LMN) involvement in …
explained by technological advances. Imaging in MND has traditionally served as a descriptive
academic tool to characterize group-level pathological features in vivo. These attempts have
been typically hampered by sample size limitations, reliance on convenience samples,
emphasis on focal structural … Spinal imaging has long been one of the least explored
frontiers of MND imaging despite disease-defining lower motor neuron (LMN) involvement in …
Summary
In addition to the technological and conceptual advances, collaborative multicentre research efforts have also gained considerable momentum. This opinion-piece reviews emerging trends in MND imaging and their implications to clinical care and drug development.
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