The circling mutant Pcdh15roda is a new mouse model for hearing loss

AA Torres, AK Rzadzinska, AF Ribeiro… - Mutation Research …, 2013 - Elsevier
Mouse mutagenesis is a key tool for studying gene function and several mutant alleles have
been described and constitute mouse models for human hereditary diseases. Genetic
hearing loss represents over 50% of all hearing loss cases in children and, due to the
heterogeneity of the disorder, there is still a demand for the isolation and characterization of
new genes and alleles. Here we report phenotypic and molecular characterization of a new
mouse model for hereditary hearing loss. The mutant rodador, isolated by Massironi and …
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