The development of the renal acidifying processes and their relation to acidosis in low-birth-weight infants
E Kerpel-Fronius, T Heim, E Sulyok - Neonatology, 1970 - karger.com
E Kerpel-Fronius, T Heim, E Sulyok
Neonatology, 1970•karger.com… The present work was designed to investigate from the 7th day of life onwards at weekly
intervals the postnatal development of the acidifying capacity of the kidney and its relation to
the acid-base parameters of the blood. These weekly results were also compared to those
found in 8 healthy full-term older infants (mean age 6.5 months), loaded with 2.8 mEq/kg of
NH4C1 and to 6 infants of the same age, loaded with 3.9 mEq/kg of NH4C1. … The Problem
of the relation of 164 Kerpel-Fronius et at: The Development of the Renal Acidifying …
intervals the postnatal development of the acidifying capacity of the kidney and its relation to
the acid-base parameters of the blood. These weekly results were also compared to those
found in 8 healthy full-term older infants (mean age 6.5 months), loaded with 2.8 mEq/kg of
NH4C1 and to 6 infants of the same age, loaded with 3.9 mEq/kg of NH4C1. … The Problem
of the relation of 164 Kerpel-Fronius et at: The Development of the Renal Acidifying …
Results The factors first to be considered in the origin of late metabolic acidosis are:(1) protein catabolism,(2) weight curve, and (3) net hydrogen ion excretion in relation to the extent of systemic acidosis.
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