The molecular basis of second messenger signaling relies on an array of proteins that
synthesize, degrade or bind the molecule to produce coherent functional outputs. Cyclic di-
GMP (c-di-GMP) has emerged as a eubacterial nucleotide second messenger regulating a
plethora of key behaviors, like the transition from planktonic cells to biofilm communities. The
striking multiplicity of c-di-GMP control modules and regulated cellular functions raised the
question of signaling specificity. Are c-di-GMP signaling routes exclusively dependent on a …

Correction: The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to
Control Pseudomonas aeruginosa Biofilm a … The correct citation is: Valentini M, Laventie
BJ, Moscoso JA, Jenal U, Filloux A (2016) The Diguanylate Cyclase HsbD Intersects with
the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility.
PLoS Genet 12(10): e1006354. doi:10.1371/journal.pgen.1006354. … Valentini M, Laventie
BJ, Moscoso J, Jenal U, Filloux A (2016) The Diguanylate Cyclase HsbD Intersects with the …