The effect of underlying clinical conditions on the risk of developing invasive pneumococcal disease in England

AJ Van Hoek, N Andrews, PA Waight, J Stowe… - Journal of Infection, 2012 - Elsevier
OBJECTIVE: To inform national policy making on the use of the 13-valent pneumococcal
vaccine among risk groups we estimated the increased risk of invasive pneumococcal
disease (IPD) outcomes among clinical risk groups. Three years of post 7-valent
pneumococcal conjugate vaccine (PCV7) data was included to investigate the herd
protection effects. METHODS: Over 22,000 IPD patients in England (March 2002–March
2009–aged 2 and over) were linked to their hospitalisation records. The prevalence of risk …
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