The efficacy of intrawound vancomycin powder and povidone-iodine irrigation to prevent surgical site infections in complex instrumented spine surgery

JVC Lemans, FC Öner, SPJ Wijdicks… - The Spine Journal, 2019 - Elsevier
BACKGROUND CONTEXT Surgical site infections (SSIs) are notorious complications in
spinal surgery and cause substantial patient morbidity. Intraoperative decontamination of the
wound with povidone-iodine irrigation or vancomycin powder has gained attention lately, but
the efficacy of either intervention is unclear. PURPOSE To determine the efficacy of
intrawound povidone-iodine or vancomycin in reducing the incidence of deep-and
superficial SSIs in instrumented spinal surgery. STUDY DESIGN/SETTING Retrospective …
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