… The precise regulation of FoxO transcription factors is … is that FoxO PTMs may act as a ‘molecular
FoxO code’ read … The effective control of FoxO activity in response to environmental …

… of FOXO proteins generate a molecular code to sense external stimuli and determine … to
the extreme diversity of the cellular roles of the FOXO proteins, the benefit of FOXO activation is …

… transcriptional specificity and constitute a Foxo 'code' 3 . Second, … on the possibility that one
of the important ways Foxo factors function in the immune system is to coregulate many of the …

… A complete knowledge on how to program the FOXO code will enable the tailoring of more
… advantage of the tumor suppressor features of FOXO proteins and at the same time avoid the …

… as for the prevention of aging by maintaining the hematopoyetic … the potential use of the
FOXO activators in these settings. Therefore, greater understanding of the regulation of FOXO …

… serve as a ‘molecular code’ to sense external stimuli and recruit it as to specific regions of
… As a result, the FOXO pathway is activated, resulting in the development of less toxic high …

… post-translational modifications have been proposed to serve as a combinatorial ‘FOXO code’,
… the role of FOXO as a prolongevity factor. Here, we discuss the role of FOXO factors in the …

… the NLS of the FOXO protein and sequester the protein in the … the NLS of the FOXO protein
and sequester the protein in the … The phosphorylation sites of PKB/Akt and SGK on FOXO …

… transcription factors is corroborated by the finding that in humans the FOXO1 gene is … -dependent
transcriptional regulation of ABCC2, which codes for the multidrug resistance-…

… The large number of modifications to the FOXO family has led to a proposed “FOXO Code,”
whereby modifications act singly or in combination to selectively recruit protein partners to …