过去一年中添加的文章，按日期排序
Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps
V Gigante, RA Alm, D Melchiorri, T Rocke… - Antimicrobial Agents …, 2024 - journals.asm.org
5 天前 - … , the World Health Organization has regularly assessed the preclinical and clinical
antibacterial development pipeline. The review identifies potential new classes of antibiotics …
antibacterial development pipeline. The review identifies potential new classes of antibiotics …
[PDF][PDF] Tuberculosis: Progress and advances in development of new drugs, treatment regimens and host-directed therapies. Article Type: Invited Review …
MJ Vjecha, M Rao, F Ntoumi, S Mfinanga, N Kapata… - academia.edu
15 天前 - … antimicrobial drug candidates are in phase 1 (Q203, TBI-166, OPC-167832, GSK
070, TBA-7371) and 5 in pre-clinical … , the current HDT development pipeline and translational …
070, TBA-7371) and 5 in pre-clinical … , the current HDT development pipeline and translational …
[HTML][HTML] The AMR brain drain
L Microbe2024 - 2024 - thelancet.com
87 天前 - … AMR diagnostics in preclinical and early clinical … antimicrobial pipeline. In response,
in 2020, the AMR Action Fund was announced with the aim of bringing 2–4 new antibiotics …
in 2020, the AMR Action Fund was announced with the aim of bringing 2–4 new antibiotics …
[HTML][HTML] Navigating the Chemical Space of ENR Inhibitors: A Comprehensive Analysis
V Kuralt, R Frlan - Antibiotics, 2024 - mdpi.com
131 天前 - … the challenges in achieving preclinical success. In our study… of compounds in
development pipelines. Furthermore, we … insights into rational antimicrobial design, seamlessly …
development pipelines. Furthermore, we … insights into rational antimicrobial design, seamlessly …
A rationally engineered small antimicrobial peptide with potent antibacterial activity
241 天前 - … few new-age antimicrobial agents are in the current developmental pipeline. Thus,
the … subjected to preclinical studies to explicitly understand and address the menace of AMR. …
the … subjected to preclinical studies to explicitly understand and address the menace of AMR. …
[PDF][PDF] Challenges and opportunities for continued access to effective antibiotics-what role for the EU?
M Anderson, D Panteli… - European Journal of Public …, 2023 - academic.oup.com
293 天前 - … securing funding for preclinical and early clinical trials, and risk significant economic
losses when launching new antibiotics. To reinvigorate the antibiotic pipeline, a holistic …
losses when launching new antibiotics. To reinvigorate the antibiotic pipeline, a holistic …
[HTML][HTML] Staph wars: the antibiotic pipeline strikes back
EJA Douglas, M Laabei - Microbiology, 2023 - microbiologyresearch.org
323 天前 - … aureus infections; and (3) an examination of the pre-clinical pipeline of anti-staphylococcal
compounds. In addition, we examine the molecular mechanism of action of novel …
compounds. In addition, we examine the molecular mechanism of action of novel …
[HTML][HTML] Challenges and opportunities for incentivising antibiotic research and development in Europe
360 天前 - … the antibiotic pipeline, there have been 12 new antibiotics … during preclinical and
clinical phases for antibiotics under … of moving an antibiotic from the preclinical research stage …
clinical phases for antibiotics under … of moving an antibiotic from the preclinical research stage …