[PDF][PDF] The homeobox HOXB13 is expressed in human minor salivary gland.
C Cazal, APV Sobral, FCS De Almeida… - Oral …, 2006 - researchgate.net
C Cazal, APV Sobral, FCS De Almeida, M Das Graças Silva‐Valenzuela, MD Durazzo…
Oral Diseases, 2006•researchgate.netBACKGROUND: Homeobox are a family of developmental genes involved in
morphogenesis and cellular differentiation. Participation of homeobox within normal and
malignant tissue has been recently discussed in the literature. OBJECTIVE: To analyze the
presence of HOXB13 transcript expression in human minor salivary gland. MATERIAL AND
METHODS: Ten-micrometer sections from frozen samples were evaluated employing
nonradioactive in situ hybridization technique and HOXB13 mRNA probes. RESULTS …
morphogenesis and cellular differentiation. Participation of homeobox within normal and
malignant tissue has been recently discussed in the literature. OBJECTIVE: To analyze the
presence of HOXB13 transcript expression in human minor salivary gland. MATERIAL AND
METHODS: Ten-micrometer sections from frozen samples were evaluated employing
nonradioactive in situ hybridization technique and HOXB13 mRNA probes. RESULTS …
BACKGROUND: Homeobox are a family of developmental genes involved in morphogenesis and cellular differentiation. Participation of homeobox within normal and malignant tissue has been recently discussed in the literature.
OBJECTIVE: To analyze the presence of HOXB13 transcript expression in human minor salivary gland. MATERIAL AND METHODS: Ten-micrometer sections from frozen samples were evaluated employing nonradioactive in situ hybridization technique and HOXB13 mRNA probes.
RESULTS: HOXB13 was found to be expressed in ducts and mucous acini but not in serous acini. CONCLUSIONS: Results suggest that HOXB13 transcripts are differently expressed in normal mucous and serous acini, and it may possibly reflect a different role in salivary gland carcinogenesis.
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