The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2

T Gassler, M Sauer, B Gasser, M Egermeier… - Nature …, 2020 - nature.com
The methylotrophic yeast Pichia pastoris is widely used in the manufacture of industrial
enzymes and pharmaceuticals. Like most biotechnological production hosts, P. pastoris is
heterotrophic and grows on organic feedstocks that have competing uses in the production
of food and animal feed. In a step toward more sustainable industrial processes, we
describe the conversion of P. pastoris into an autotroph that grows on CO2. By addition of
eight heterologous genes and deletion of three native genes, we engineer the peroxisomal …

[引用][C] The Industrial Yeast Pichia pastoris Is Converted from a Heterotroph into an Autotroph Capable of Growth on CO2

M Steiger - 2023 - repositum.tuwien.at
reposiTUm: The Industrial Yeast Pichia pastoris Is Converted from a Heterotroph into an
Autotroph Capable of Growth on CO2 … The Industrial Yeast Pichia pastoris Is Converted
from a Heterotroph into an Autotroph Capable of Growth on CO2 … CO2, Pichia pastoris,
methanol assimilation, peroxisome …
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