The lipid droplet as a signaling node
Lipid droplets are widely recognized as the primary energy storage depot in most cell types.
However, as the field of lipid droplet biology has grown, roles for these dynamic organelles
have expanded beyond storage of lipids. These studies show that lipid droplets orchestrate
numerous signaling cascades as a means to govern cellular function and disease
development. Moreover, lipid droplets elicit these effects through changes in the
sequestration and production of signaling lipids as well as influencing proteins that coat the …
However, as the field of lipid droplet biology has grown, roles for these dynamic organelles
have expanded beyond storage of lipids. These studies show that lipid droplets orchestrate
numerous signaling cascades as a means to govern cellular function and disease
development. Moreover, lipid droplets elicit these effects through changes in the
sequestration and production of signaling lipids as well as influencing proteins that coat the …
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