… said, the supergene, the major histocompatibility complex (MHC), is like a page from the nature
book read outside of the … We would here like to recall the evolution of concepts regarding …

… describe the organization of the genes in the MHC and discuss how the variation in MHC
molecules arises. We will also see how the effect of polygeny and polymorphism on the range …

… Some of the Mhc loci are highly polymorphic, while … the genetic organization of the Mhc in
different species and will discuss the selection pressures acting on the individual loci and the …

… the natural history of the genes involved in present-day major histocompatibility complex (MHC)
function and to understand how this new function emerged, we first redefine the …

… THE MAJOR HISTOCOMPATIBILITY complex (MHC) is an extended cluster of genes … the
number and importance of the immunological functions they encode. Historically, interest in the …

… The major histocompatibility complex (MHC) has become a … Here, we review the contribution
of studies on the MHC in non… influence the tempo and mode of evolution at the MHC, and …

… MHC suggested very strongly that the gene product, then completely … to the known genes
within the major histocompatibility complex. However, the striking antigenic specificity of the Ir-1 …

… reviewed previously by many authors, the present paper has been written in an attempt to
focus on the class II region of the major histocompatibility complex in bovines namely cattle, …

… to include many genes responsible for coordinating the immune response. It is named the
histocompatibility complex because it was first identified as the site of numerous genes that …

… of the important components of the immune system, the major histocompatibility complex (…
cells that ingest infectious microorganisms or the self-cells infected with microorganism. On …