In the current study, it has been identified that white oleander is impossible or difficult-to-root (0.00%) while, pink oleander is slightly difficult-to-root cuttings (6.67%) in absence of supplied auxin (treated with distilled water). However, to improve the capability of rooting response of white oleander cuttings (difficult-to-root variety), six treatments have been employed including identified (eg. o-coumaric acid) and un-identified co-factors (eg whitetope seeds extract), individually and in combination with IBA and the results revealed the followings:-• Some of these treatments were at high level of significance (P0. 05), verifying an original successful and economical acceptance by vegetative propagation of difficult-to-root cuttings (white oleander) that caused (induced) to root and increased vegetative traits, when supplied individually or in combination with IBA, the highest values are represented in the following treatments:-