Background Mismatch negativity (MMN) is an extensively validated biomarker of cognitive
function across both normative and clinical populations and has previously been localized to
supratemporal auditory cortex. MMN is thought to represent a comparison of the features of
the present stimulus versus a mnemonic template formed by the prior stimuli. Methods We
used concurrent thalamic and primary auditory cortical (A1) laminar recordings in 7
macaques to evaluate the relative contributions of core (lemniscal) and matrix …