Irritability refers to a proneness for anger, and is a symptom of internalizing and externalizing
psychopathology. Since irritability is associated with significant cross-sectional and
longitudinal impairments, research on the behavioral and neural correlates of pediatric
irritability in populations at risk for significant irritability is of paramount importance. Irritability
can be assessed in the laboratory using behavioral paradigms that elicit frustration. Few
behavioral frustration paradigms have been designed to measure the effects of frustration on …