Objective To evaluate the efficacy, pharmacokinetics, immunogenicity, and safety of multiple
infusions of a chimeric monoclonal anti‐tumor necrosis factor α antibody (cA2)(infliximab;
Remicade, Centocor, Malvern, PA) given alone or in combination with low‐dose
methotrexate (MTX) in rheumatoid arthritis (RA) patients. Methods In a 26‐week, double‐
blind, placebo‐controlled, multicenter trial, 101 patients with active RA exhibiting an
incomplete response or flare of disease activity while receiving low‐dose MTX were …

Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha
antibody combined with low-dose weekly methotrexate in rheumatoid arthritis | CiNii
Research … Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis
factor alpha antibody combined with low-dose weekly methotrexate in rheumatoid arthritis …