Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets

M Ettinger, T Burner, A Sharma, YT Chang… - Nature …, 2023 - nature.com
… lesions in detail and to identify new therapeutic targets. Using gene and protein … cytokines
and increased numbers of Th17 cells in six DD patients. We provide evidence that targeting

Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

T Hideshima, C Mitsiades, G Tonon… - Nature Reviews …, 2007 - nature.com
… to conventional therapies. Although multiple myeloma remains incurable, novel targeted
agents, … the framework for new prognostic classification and identifying new therapeutic targets. …

[图书][B] Cytokines as potential therapeutic targets for inflammatory skin diseases

R Numerof, CA Dinarello, K Asadullah - 2007 - Springer
Cytokines are now far beyond the stage when they were of … cytokine-directed therapies
are already being employed as part of the clinical practice. Strategies for neutralizing cytokines

Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets

D Ezhilarasan, E Sokal, M Najimi - Hepatobiliary & Pancreatic Diseases …, 2018 - Elsevier
… The aHSCs in the injured liver is responsive to several profibrogenic cytokines. Therefore,
in vitro studies targeted these cytokines with their specific inhibitors and claimed that it has the …

The pathogenesis of sepsis and potential therapeutic targets

M Huang, S Cai, J Su - International journal of molecular sciences, 2019 - mdpi.com
… a range of pro-inflammatory cytokines, and this can trigger cytokine storms and activate the
… These events are followed by the production of inflammatory cytokines such as interleukin (…

Novel therapeutic targets in rheumatoid arthritis

MI Koenders, WB van den Berg - Trends in pharmacological sciences, 2015 - cell.com
cytokine stimulation. Natural inhibitor suppressor of cytokine signaling proteins (SOCS)
or therapeutic … population of patients with RA with tailor-made therapy targeting the IL-17/IL-17R …

Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation

A Paniri, H Akhavan-Niaki - Life Sciences, 2020 - Elsevier
… implicated in inflammatory cytokine storm and inflammatory … drugs to target inflammatory
cytokines especially IL-6 and … new prognostic biomarkers and therapeutic targets in treatment of …

Cytokines and their receptors as therapeutic targets in asthma.

RA Pauwels, GG Brusselle… - Clinical & …, 1998 - search.ebscohost.com
cytokines results in biological effects that are of potential interest for the human disease. We
intend to review potential cytokine tar… the role of different cytokines in the development of IgE-…

[PDF][PDF] From basic science to clinical practice: use of cytokines and chemokines as therapeutic targets in renal diseases

P Romagnani - Journal of Nephrology, 2005 - Citeseer
… Recently, several cytokines have been suggested as possible therapeutic targets in renal
diseases, and their possible clinical utility is now being tested in phase I-II clinical trials. …

[PDF][PDF] Adipose tissue-derived cytokines, CTRPs as biomarkers and therapeutic targets in metabolism and the cardiovascular system

YJ Wang, JL Zhao, WB Lau, J Liu, R Guo, XL Ma - Vessel Plus, 2017 - f.oaes.cc
… Adipose tissue-derived cytokines including the C1q/tumor … potent biomarkers or therapeutic
targets for modulating metabolic … potential of CTRPs as biomarkers and therapeutic targets. …