Thyroid autoimmunity as a window to autoimmunity: an explanation for sex differences in the prevalence of thyroid autoimmunity
SJ Merrill, Y Mu - Journal of theoretical biology, 2015 - Elsevier
Autoimmune thyroid diseases (AITDs), predominately Graves׳ disease and Hashimoto׳ s
thyroiditis, comprise the most common autoimmune diseases in humans. Both have the
production of anti-thyroid antibody as an important aspect and both are much more
prevalent in females, being at least 10 times more common than in males. Using these two
clues, a hypothesis for the initiation of thyroid autoimmunity is proposed that helps to make
the case that the thyroid is one of the most sensitive sites for autoimmunity and helps …
thyroiditis, comprise the most common autoimmune diseases in humans. Both have the
production of anti-thyroid antibody as an important aspect and both are much more
prevalent in females, being at least 10 times more common than in males. Using these two
clues, a hypothesis for the initiation of thyroid autoimmunity is proposed that helps to make
the case that the thyroid is one of the most sensitive sites for autoimmunity and helps …