Time to antibiotic administration independently predicts survival from severe sepsis in patients treated according to the surviving sepsis guidelines
GJ Fulda, M Zubrow, T Dahanayake, D Mahoney… - Chest, 2007 - journal.chestnet.org
PURPOSE: The mortality of severe sepsis exceeds 40%. Recently, the treatment of severe
sepsis has focused on management guidelines which incorporate multiple therapeutic
approaches. These guidelines include algorithms for resuscitation, vasopressors, antibiotic
administration, blood transfusions, rhAPC, and glucose control. In 2005 our institution
adopted the “surviving sepsis guidelines” to treat severe sepsis. When utilizing a
multimodality approach, the effect of each individual therapy on outcome is unknown. The …
sepsis has focused on management guidelines which incorporate multiple therapeutic
approaches. These guidelines include algorithms for resuscitation, vasopressors, antibiotic
administration, blood transfusions, rhAPC, and glucose control. In 2005 our institution
adopted the “surviving sepsis guidelines” to treat severe sepsis. When utilizing a
multimodality approach, the effect of each individual therapy on outcome is unknown. The …
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