[引用][C] Total synthesis of muconin by efficient assembly of chiral building blocks
SE Schaus, J Brånalt, EN Jacobsen - The Journal of Organic …, 1998 - ACS Publications
Muconin (1) is a novel tetrahydropyran-bearing acetogenin isolated from Rollinia mucosa
that has exhibited potent and selective in vitro cytotoxicities against pancreatic and breast
tumor cell lines. 1 We considered the possibility of preparing 1 by the convergent assembly
of readily accessible chiral units (Scheme 1). We describe herein the total synthesis of
muconinsthe first of any THP-bearing Annonaceous acetogenin2sby taking advantage of
such a chiral building block approach.
that has exhibited potent and selective in vitro cytotoxicities against pancreatic and breast
tumor cell lines. 1 We considered the possibility of preparing 1 by the convergent assembly
of readily accessible chiral units (Scheme 1). We describe herein the total synthesis of
muconinsthe first of any THP-bearing Annonaceous acetogenin2sby taking advantage of
such a chiral building block approach.
Total synthesis of muconin by efficient assembly of chiral building blocks
JD Schloss, LA Paquette, S Schaus, J Brånalt… - …, 1999 - keio.elsevierpure.com
Total synthesis of muconin by efficient assembly of chiral building blocks — Keio University …
Total synthesis of muconin by efficient assembly of chiral building blocks …
Total synthesis of muconin by efficient assembly of chiral building blocks …
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