Toward risk-stratified breast cancer screening: considerations for changes in screening guidelines
Populationwide breast cancer screening programs have been established in many countries
to reduce breast cancer mortality through early detection and treatment. These programs
offer routine mammographic screening to women at average risk starting at age 40 to 50
years with frequency of 1 to 3 years and enhanced screening starting at earlier ages to
women at elevated risk owing to family history or genetic susceptibility from highpenetrance
genetic mutations (eg, inBRCA1/2orTP53). 1 Screening guidelines recommend different …
to reduce breast cancer mortality through early detection and treatment. These programs
offer routine mammographic screening to women at average risk starting at age 40 to 50
years with frequency of 1 to 3 years and enhanced screening starting at earlier ages to
women at elevated risk owing to family history or genetic susceptibility from highpenetrance
genetic mutations (eg, inBRCA1/2orTP53). 1 Screening guidelines recommend different …