Toward the elimination of schistosomiasis
CH King - New England Journal of Medicine, 2009 - Mass Medical Soc
New England Journal of Medicine, 2009•Mass Medical Soc
… In the 1980s, after the introduction of the highly effective antischistosomal drug
praziquantel, it was believed that large-scale drug delivery through school-based or
community-based programs could solve the problem of schistosomiasis transmission and,
in so doing, eliminate the risk of parasite-associated disease. Although such mass-treatment
campaigns substantially reduced the infectious burden and the parasite-associated
morbidity, they often failed to curb parasite transmission in high-risk communities. Since …
praziquantel, it was believed that large-scale drug delivery through school-based or
community-based programs could solve the problem of schistosomiasis transmission and,
in so doing, eliminate the risk of parasite-associated disease. Although such mass-treatment
campaigns substantially reduced the infectious burden and the parasite-associated
morbidity, they often failed to curb parasite transmission in high-risk communities. Since …
Schistosomiasis remains one of the world's most prevalent diseases. Dr. Charles King discusses how we can break the cycle of transmission.
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