[HTML][HTML] Transcriptomic data helps refining classification of pulmonary carcinoid tumors with increased mitotic counts
O Sazonova, V Manem, M Orain… - Modern Pathology, 2020 - Elsevier
Pulmonary neuroendocrine neoplasms are classified by WHO as either typical or atypical
carcinoids, large cell (LCNEC) or small cell (SCLC) neuroendocrine carcinoma based on
mitotic count, morphology, and necrosis assessment. LCNEC with low mitotic count and
sharing morphologic features with carcinoids are in a gray zone for classification and their
rare prevalence and the paucity of studies precludes proper validation of the current grading
system. In this study, we aim to investigate their clinicopathological and transcriptomic …
carcinoids, large cell (LCNEC) or small cell (SCLC) neuroendocrine carcinoma based on
mitotic count, morphology, and necrosis assessment. LCNEC with low mitotic count and
sharing morphologic features with carcinoids are in a gray zone for classification and their
rare prevalence and the paucity of studies precludes proper validation of the current grading
system. In this study, we aim to investigate their clinicopathological and transcriptomic …
以上显示的是最相近的搜索结果。 查看全部搜索结果