… some macromolecules that have been associated to the systems and the modality of
administration for which we have tested them as carriers for transmucosal macromolecular drugs. …

… In this section, the latest advances in the transmucosal delivery of hydrophilic macromolecules
will be covered, focusing mainly on nasal and oral administration. The authors are aware …

… encountered for macromolecular drugs. … transmucosal barriers for drug delivery, nasal,
buccal, rectal, ocular, pulmonary, and vaginal mucosa. The author believes that transmucosal …

… examples of a macromolecular drug. Most patients suffering … enhancers acting on a
particular drug delivery route, but this … in different transmucosal drug delivery systems including …

… route for the systemic delivery of macromolecular drugs (peptides and proteins) [6].
Nevertheless, the oral transmucosal route has some disadvantages mainly related to the low …

… routes are considered as most attractive drug delivery sites for oromucosal delivery of …
derivatives on release and transmucosal penetration of various macromolecules such as insulin […

… sublingual drug delivery. Particular attention is given to new approaches which can extend
dosage form retention time or can be engineered to deliver … of transmucosal delivery systems. …

… Key words: Buccal delivery; Transmucosal delivery; Low … delivery of macromolecular drugs
represents one of the greatest challenges in pharmaceutical sciences. Transmucosal delivery …

… oral delivery systems for therapeutic macromolecules is … drug delivery technologies. This
offers an optimistic perspective on the potential clinical usage of oral macromolecular drugs…

… Significant advances in transmucosal drug delivery have recently been made and have …
mucus is of great value in the design of efficient drug delivery systems. Mucins, the primary non-…