purpose. To investigate the coding exons in the trabecular meshwork–induced
glucocorticoid response protein (TIGR) gene for mutations in primary open-angle glaucoma
(POAG) in Chinese subjects. methods. Ninety-one Chinese patients with POAG and 113 of
their family members without glaucoma were screened for sequence alterations in the TIGR
gene by polymerase chain reaction, conformation-sensitive gel electrophoresis, and DNA
sequencing. One hundred thirty-two unrelated individuals without glaucoma, aged 50 years …

Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma
| CiNii Research … Truncations in the TIGR gene in individuals with and without primary
open-angle glaucoma …