Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: Antihypertensive role of amaranth peptides
APB de la Rosa, AB Montoya, P Martínez-Cuevas… - Nitric Oxide, 2010 - Elsevier
Amaranth seed proteins have a better balance of essential amino acids than cereals and
legumes. In addition, the tryptic hydrolysis of amaranth proteins generates, among other
peptides, angiotensin converting enzyme (ACE) inhibitory (ACEi) peptides. ACE converts
angiotensin I (Ang I) into Ang II, but is also responsible for the degradation of bradykinin
(BK). In contrast to Ang II, BK stimulates vasodilation modulated through endothelial nitric
oxide (NO) production. The aim of the present study was to characterize the ACEi activity of …
legumes. In addition, the tryptic hydrolysis of amaranth proteins generates, among other
peptides, angiotensin converting enzyme (ACE) inhibitory (ACEi) peptides. ACE converts
angiotensin I (Ang I) into Ang II, but is also responsible for the degradation of bradykinin
(BK). In contrast to Ang II, BK stimulates vasodilation modulated through endothelial nitric
oxide (NO) production. The aim of the present study was to characterize the ACEi activity of …
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