Tumoricidal effects of unprimed and curcumin-primed adipose-derived stem cells on human hepatoma HepG2 cells under oxidative conditions
Introduction Adipose-derived stem cells (ASCs) have been proven to have tumoricidal
effects against hepatic cancer cell lines. However, it appears that exposure to oxidative
microenvironment compromises the potential outcome of ASCs in real hepatoma. Herein,
we aimed to examine the tumoricidal effects of ASCs under oxidative conditions and to
investigate the impact of curcumin priming on ASCs' therapeutic potential. Methods We used
human hepatoma (HepG2) cells in a coculture system with unprimed or curcumin-primed …
effects against hepatic cancer cell lines. However, it appears that exposure to oxidative
microenvironment compromises the potential outcome of ASCs in real hepatoma. Herein,
we aimed to examine the tumoricidal effects of ASCs under oxidative conditions and to
investigate the impact of curcumin priming on ASCs' therapeutic potential. Methods We used
human hepatoma (HepG2) cells in a coculture system with unprimed or curcumin-primed …
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