Experimental studies have shown that rats exposed to ultrafine particles of, for example,
titanium dioxide or carbon black, sustain more lung injury and pathology than rats exposed
to the same deposited mass of fine respirable particles composed of the same material.
Epidemiological studies have shown a correlation between environmental particulate air
pollution (PM10) and a range of endpoints of lung morbidity and also mortality, and an
ultrafine fraction of the PM10 particles is considered to be the principal mediator of these …