Ultrasound backscatter imaging provides frequency-dependent information on structure, composition and mechanical properties of human trabecular bone

JP Karjalainen, J Töyräs, O Riekkinen… - Ultrasound in medicine …, 2009 - Elsevier
The strength as well as the acoustic properties of trabecular bone are determined by its
structure and composition. Consequently, tissue structure and compositional properties also
affect the ultrasound propagation in bone. The diagnostic potential of ultrasound has not
been fully exploited in clinical quantitative ultrasound devices. The aim of this study was to
investigate the ability of quantitative ultrasound pulse-echo imaging, conducted over a broad
range of frequencies (1 to 5 MHz), to predict the mechanics, composition and microstructure …
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