Stemming in part from the lack of theory, predictors of the relationship between neighborhoods and intimate partner violence (IPV) are underidentified. Furthermore, few mediation studies exist that inductively build and deductively confirm theoretical frameworks. This article provides an integrative review of the literature, aiming to enhance the field’s understanding of predictors and potential mechanisms that drive this relationship, using a combined theoretical model to guide the analysis. The integrative review was conducted using Whittemore and Knafl’s systematic method for integrative reviews with articles published between 1995 and 2015. Findings indicate that macro-, exo-, and mesolevel predictors and mediators in the proposed model have modest empirical support; however, a number of concepts at each ecological level have yet to be fully researched. Results of this review suggest that a well-defined and integrative theoretical framework will enhance the current understanding of ecological research into IPV. Additionally, a comprehensive ecological approach to IPV intervention is likely to be more effective than employing solely an individual-level approach. Intervention implications are discussed.