Although Pneumocystis infection might be one of the causes of secondary pulmonary
alveolar proteinosis (PAP), the mechanism of its pathogenesis is uncertain. We analyzed a
mouse model of secondary PAP resulting from Pneumocystis infection using mice deficient
in CD40 (CD40KO), and evaluated the mechanism of the pathogenesis of secondary PAP
from the viewpoint of surfactant-associated protein (SP) homeostasis, the overproduction of
SP by type II alveolar epithelial cells, and the phagocytic function of alveolar macrophages …

CiNii 博士論文 - Up-regulation of surfactant protein production in a mouse model of
secondary pulmonary alveolar proteinosis … Up-regulation of surfactant protein production
in a mouse model of secondary pulmonary alveolar proteinosis 続発性肺胞蛋白症のマウス
モデルにおけるサーファクタントプロテインの産生亢進 … Up-regulation of surfactant protein
production in a mouse model of secondary pulmonary alveolar proteinosis …