Use of apixaban in children awaiting heart transplantation

V Benvenuto, C Hartje‐Dunn, L Vo… - Pediatric …, 2024 - Wiley Online Library
Background The use of apixaban in the pediatric cardiac population is expanding. We
describe our apixaban dosing and monitoring strategy in children and young adults awaiting
heart transplantation, along with outcomes related to bleeding and thrombosis during wait‐
list and early post‐transplant periods. Methods This study is a retrospective, single‐center
analysis of all patients receiving apixaban while awaiting cardiac transplantation. Weight‐
based dosing was monitored with peak drug‐specific anti‐Xa chromogenic analysis …

Use of Apixaban in Children Awaiting Heart Transplantation for Thromboprophylaxis

V Benvenuto, C Hartje-Dunn, L Vo, A Hellinger… - The Journal of Heart and …, 2023 - Elsevier
Purpose The use of apixaban in the pediatric cardiac population is expanding. We describe
our apixaban dosing and monitoring strategy in children and young adults awaiting heart
transplantation and outcomes related to bleeding and thrombosis during wait-list and early
post-transplant periods. Methods Retrospective, single center analysis of all patients on
apixaban awaiting cardiac transplantation. Weight based dosing was monitored with peak
drug-specific anti-Xa chromogenic analysis (apixaban levels). Goal apixaban peak levels …
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