[HTML][HTML] Using the Drosophila Transcriptional Reporter of Intracellular Calcium (TRIC) to examine lasting ethanol-induced changes in neuroexcitability
K Merriman, E Petruccelli - Micropublication Biology, 2021 - ncbi.nlm.nih.gov
K Merriman, E Petruccelli
Micropublication Biology, 2021•ncbi.nlm.nih.govThe Drosophila transcriptional reporter of intracellular calcium (TRIC) is a genetic tool used
to measure lasting changes in neuroexcitability. Both pan-neuronal and dopaminergic cells
were examined with TRIC to test the hypothesis that ethanol exposure causes lasting
changes in adult brain neuroexcitability. We found little to no impact on TRIC signal
following acute and repeated ethanol vapor exposures. This work shows that TRIC may be
useful in future investigations such as developmental or chronic drug exposure paradigms.
to measure lasting changes in neuroexcitability. Both pan-neuronal and dopaminergic cells
were examined with TRIC to test the hypothesis that ethanol exposure causes lasting
changes in adult brain neuroexcitability. We found little to no impact on TRIC signal
following acute and repeated ethanol vapor exposures. This work shows that TRIC may be
useful in future investigations such as developmental or chronic drug exposure paradigms.
Abstract
The Drosophila transcriptional reporter of intracellular calcium (TRIC) is a genetic tool used to measure lasting changes in neuroexcitability. Both pan-neuronal and dopaminergic cells were examined with TRIC to test the hypothesis that ethanol exposure causes lasting changes in adult brain neuroexcitability. We found little to no impact on TRIC signal following acute and repeated ethanol vapor exposures. This work shows that TRIC may be useful in future investigations such as developmental or chronic drug exposure paradigms.
ncbi.nlm.nih.gov
以上显示的是最相近的搜索结果。 查看全部搜索结果