Various penA mutations together with mtrR, porB and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
SG Lee, H Lee, SH Jeong, D Yong… - Journal of …, 2010 - academic.oup.com
Objectives To examine mutations within the penA, mtrR, porB, ponA and pilQ genes of
Neisseria gonorrhoeae to determine their contribution to cephalosporin resistance. Methods
A total of 46 N. gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
(MICs≥ 0.12 mg/L) and two susceptible isolates were selected. The full sequence of penA
and partial sequences previously reported as hot mutation sites of the other genes were
analysed. Genotyping by N. gonorrhoeae multiantigen sequence typing (NG-MAST) was …
Neisseria gonorrhoeae to determine their contribution to cephalosporin resistance. Methods
A total of 46 N. gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
(MICs≥ 0.12 mg/L) and two susceptible isolates were selected. The full sequence of penA
and partial sequences previously reported as hot mutation sites of the other genes were
analysed. Genotyping by N. gonorrhoeae multiantigen sequence typing (NG-MAST) was …
Various penA mutations together with mtrR, porB and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone.
LSG Lee SangGuk, LHM Lee HyukMin… - 2010 - cabidigitallibrary.org
Objectives: To examine mutations within the penA, mtrR, porB, ponA and pilQ genes of
Neisseria gonorrhoeae to determine their contribution to cephalosporin resistance. Methods:
A total of 46 N. gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
(MICs≥ 0.12 mg/L) and two susceptible isolates were selected. The full sequence of penA
and partial sequences previously reported as hot mutation sites of the other genes were
analysed. Genotyping by N. gonorrhoeae multiantigen sequence typing (NG-MAST) was …
Neisseria gonorrhoeae to determine their contribution to cephalosporin resistance. Methods:
A total of 46 N. gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
(MICs≥ 0.12 mg/L) and two susceptible isolates were selected. The full sequence of penA
and partial sequences previously reported as hot mutation sites of the other genes were
analysed. Genotyping by N. gonorrhoeae multiantigen sequence typing (NG-MAST) was …
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