Vedolizumab concentrations in the breast milk of nursing mothers with inflammatory bowel disease
M Julsgaard, J Kjeldsen, BM Bibby, B Brock… - …, 2018 - gastrojournal.org
Dear Editors: Vedolizumab, a monoclonal immunoglobulin (Ig) G1 antibody, has a favorable
safety profile in nonpregnant and nonlactating patients. 1 The data on the safety of
vedolizumab in reproduction is limited, 2, 3 with currently none available in lactating
mothers. Before vedolizumab infusion, a breastmilk and a serum trough sample were
collected from 5 mothers with inflammatory bowel disease (IBD) who were intentionally, fully
breastfeeding their infants despite the lack of safety data. Thirty minutes after the infusion …
safety profile in nonpregnant and nonlactating patients. 1 The data on the safety of
vedolizumab in reproduction is limited, 2, 3 with currently none available in lactating
mothers. Before vedolizumab infusion, a breastmilk and a serum trough sample were
collected from 5 mothers with inflammatory bowel disease (IBD) who were intentionally, fully
breastfeeding their infants despite the lack of safety data. Thirty minutes after the infusion …
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