[PDF][PDF] Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases

V Calabrese, C Cornelius, C Mancuso, E Barone… - Front …, 2009 - article.imrpress.com
Front Biosci, 2009article.imrpress.com
Dietary antioxidants, such as curcumin, Lcarnitine/acetyl-L-carnitine and carnosine have
recently been demonstrated in vitro to be neuroprotective through the activation of hormetic
pathways, including vitagenes. In the present review we discuss the importance of
vitagenes in the cellular stress response and analyse, from a pharmacological point of view,
the potential use of dietary antioxidants in the treatment of neurodegenerative disorders in
humans. … Here we priviledge the term of vitagene, rather than the more general biological …
Abstract
Introduction 3. The vitagene family 3.1. Heme oxygenase-1 3.2. Heat shock protein 70 3.3. Thioredoxin/Thioredoxin reductase 4. Natural antioxidants and neurodegenerative disorders 4.1. Curcumin
article.imrpress.com
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