Vitamin B6 versus mianserin and placebo in acute neuroleptic-induced akathisia: a randomized, double-blind, controlled study
C Miodownik, V Lerner, N Statsenko… - Clinical …, 2006 - journals.lww.com
Treatment strategies against acute neuroleptic-induced akathisia (NIA) include
anticholinergic (antimuscarinic) agents, dopamine agonists, GABAergic agents, β-blockers,
benzodiazepines, and serotonin antagonists. However, many patients who have acute
akathisia fail to respond. In previous studies, mianserin and vitamin B 6 were found to be
effective in the treatment of acute akathisia. The purpose of this study was to compare the
efficacy of B 6, mianserin and placebo in the treatment of acute NIA. Sixty schizophrenia and …
anticholinergic (antimuscarinic) agents, dopamine agonists, GABAergic agents, β-blockers,
benzodiazepines, and serotonin antagonists. However, many patients who have acute
akathisia fail to respond. In previous studies, mianserin and vitamin B 6 were found to be
effective in the treatment of acute akathisia. The purpose of this study was to compare the
efficacy of B 6, mianserin and placebo in the treatment of acute NIA. Sixty schizophrenia and …
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