Background: Syphilis is a systemic disease from the outset and is caused by the spirochaete
Treponema pallidum. The … Acquired syphilis is divided into early and late syphilis. Early …

… Ever since syphilis was ®rst described its treatment has caused controversy. Despite
Fracastoro’s claim, the ®rst effective cure for syphilis (Treponema pallidum subsp pallidum) was …

… and management of syphilis in … Treponema pallidum subspecies pallidum, new
treponemal tests, and rapid-point-of-care (POC) tests detecting both treponemal and non-treponemal …

… The etiologic agent Treponema pallidum has never been … The disease has been effectively
treated with penicillin since 1943… Treponema pallidum subsp pallidum, which causes syphilis, …

… • The IgG immunoblot for Treponema pallidum has no added major … of Treponema pallidum
PCR testing in early syphilis. BMC … Diagnosing Treponema pallidum in secondary syphilis by …

… (c) The diagnosis of neurosyphilis is confirmed by the subsequent detection of intrathecal
production of antibodies against Treponema pallidum. (d) In neurosyphilis, treatment with …

The present review summarises the current knowledge in the field of syphilis diagnosis and
treatment, along with epidemiologic and historical data. A literature search was conducted in …

… for all stages of syphilis. The emergence of clinically significant azithromycin resistance
in Treponema pallidum subsp. pallidum, the syphilis agent, has resulted in treatment failures, …

… or x-ray evidence of syphilis infection). We compared the … guidelines for the treatment of
Treponema pallidum (syphilis) and the 2017 guidelines for syphilis screening and treatment …

… We used the following search terms: “Treponema pallidum” or “treponemal infections/ therapy.”
Reference lists of the retrieved articles were also manually searched for other potentially …