Waist‐to‐height ratio as a risk marker for metabolic syndrome in childhood. A meta‐analysis

C Ochoa Sangrador, J Ochoa‐Brezmes - Pediatric obesity, 2018 - Wiley Online Library
C Ochoa Sangrador, J Ochoa‐Brezmes
Pediatric obesity, 2018Wiley Online Library
Background Individuals with abdominal obesity have a higher cardiovascular risk,
regardless of the degree of global overweight. Objective To estimate the accuracy of the
Waist/height ratio (WtHR) as a risk marker for metabolic syndrome (MS) in children or
adolescents. Methods Published cohort or cross‐sectional studies (Pubmed, Embase‐
SCOPUS and CINAHL) were searched, with no limits of time. Studies providing Waist/height
ratio and clustered criteria of metabolic syndrome were included. Results Thirty‐one studies …
Background
Individuals with abdominal obesity have a higher cardiovascular risk, regardless of the degree of global overweight.
Objective
To estimate the accuracy of the Waist/height ratio (WtHR) as a risk marker for metabolic syndrome (MS) in children or adolescents.
Methods
Published cohort or cross‐sectional studies (Pubmed, Embase‐SCOPUS and CINAHL) were searched, with no limits of time. Studies providing Waist/height ratio and clustered criteria of metabolic syndrome were included.
Results
Thirty‐one studies (66,912 subjects) were selected. Overall, a high WtHR (≥0.5) was associated with a four‐fold increased risk of clustered criteria of MS (odds ratio [OR] 4.15, 95% confidence interval [95% CI]: 2.69 to 6.42) and two‐fold increased risk when adjusted by general obesity (adjusted OR 2.26, 95% CI: 1.29 to 3.98). The WtHR, as a quantitative measure, showed a pooled area under the curve of 0.76 (95% CI: 0.71 to 0.80) and, as a dichotomous measure, with a cut‐off point close to 0.5, a sensitivity of 60% (95% CI: 50% to 68.8%) and a specificity of 79% (95% CI: 71.6% to 83.9%).
Conclusions
Measuring WtHR may be considered in regular health checks of children and adolescents, as it can measure cardiovascular risk regardless of the degree of general obesity.
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